El Caguán DMZ (1999–2002) was a demilitarized zone of 42,000 km² in southern Colombia authorized by the government of President Andrés Pastrana to negotiate a peace process with the Revolutionary Armed Forces of Colombia (FARC-EP).
On October 8, 1998, then presidential candidate Andrés Pastrana agreed with FARC commanders to create a demilitarized zone in the region of El Caguán river basin, a jungle region in south central Colombia made up by the municipalities of Vista Hermosa, La Macarena, La Uribe and Mesetas in Meta Department, and San Vicente del Caguán in Caquetá Department to negotiate a possible peace process.